⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312925 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL65989 | 0.69 | LMNA (0.30) | — | |
| SCHEMBL5494372 | 0.64 | LMNA (0.39) | — | |
| SCHEMBL483640 | 0.64 | FDPS (0.48) | — | |
| SCHEMBL53350 | 0.63 | LPAR3 (0.41) | — | |
| SCHEMBL51438 | 0.63 | LPAR3 (0.41) | — | |
| SCHEMBL52944 | 0.63 | LPAR3 (0.41) | — | |
| SCHEMBL53001 | 0.63 | LPAR3 (0.41) | — | |
| SCHEMBL52249 | 0.63 | LPAR3 (0.41) | — | |
| SCHEMBL52486 | 0.63 | LPAR3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273740-A1 | Phospholipids for the Treatment of Infection by Togaviruses, Herpes Viruses and Coronaviruses | FLEMING RONALD A | 2010-10-28 | — | — | US | disclosed |
| WO-2005099719-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050187191-A1 | Methods and compositions for the treatment of respiratory syncytial virus | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-08-25 | — | — | US | disclosed |
| US-20050187192-A1 | Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses | KUCERA PHARMACEUTICAL COMPANY | 2005-08-25 | — | — | US | disclosed |