SCHEMBL3263270

SCHEMBL3263270

[CH2]CC([CH2])C1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.40
SHBG P04278 1/20 0.40
TP53 P04637 2/20 0.37
LMNA P02545 2/20 0.36
KDM4E B2RXH2 2/20 0.36
GMNN O75496 1/20 0.36
MAPT P10636 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 3/20 0.31
CYP2D6 P10635 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
MLNR O43193 1/20 0.31
ABCB11 O95342 1/20 0.31
EGFR P00533 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9204742 0.97
SCHEMBL9213591 0.79 EPHX1 (0.37) EPHX1SHBGTP53LMNAKDM4E
SCHEMBL2185225 0.76 EPHX1 (0.56) EPHX1SHBGTP53LMNAKDM4E
SCHEMBL892135 0.76 SHBG (0.56) EPHX1SHBGTP53LMNAKDM4E
SCHEMBL969704 0.76 SHBG (0.56) EPHX1SHBGTP53LMNAKDM4E
SCHEMBL7507782 0.76 TP53 (0.41) EPHX1SHBGTP53LMNAKDM4E
SCHEMBL1193182 0.76 SHBG (0.56) EPHX1SHBGTP53LMNAKDM4E
SCHEMBL9213385 0.76 EPHX1 (0.33) EPHX1SHBGTP53LMNAKDM4E
SCHEMBL9206468 0.75 EPHX1 (0.34) EPHX1SHBGTP53LMNAKDM4E
SCHEMBL9213980 0.74 EPHX1 (0.42) EPHX1SHBGTP53LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0430800-B1 Substituted benzothiazolinones, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1995-01-25 EP claimed
US-5084469-A Analgesics ADIR ET COMPAGNIE (FR) 1992-01-28 US claimed
EP-1952184-B1 PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE TRANSITIONS OPTICAL INC (US) 2021-08-11 EP disclosed
EP-1666504-B1 Use of maleimide derivatives in water compatible energy curable compositions SUN CHEMICAL CORP (US) 2010-09-08 EP disclosed
US-7649027-B2 having juts via photopolymerization in supercritical carbon dioxide; calcining KANSAI PAINT CO., LTD. (JP) 2010-01-19 US disclosed
US-20090023830-A1 POLYMER AND PROCESS FOR PRODUCING POLYMER KANSAI PAINT CO., LTD. (JP) 2009-01-22 US disclosed
EP-1952184-A2 PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE TRANSITIONS OPTICAL, INC. (US) 2008-08-06 EP disclosed
US-7258437-B2 Photochromic multifocal optical article TRANSITIONS OPTICAL, INC. (US) 2007-08-21 US disclosed
WO-2007030352-A2 PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE TRANSITIONS OPTICAL, INC. (US) 2007-03-15 WO disclosed
US-20070052922-A1 Photochromic multifocal optical article TRANSITIONS OPTICAL LIMITED (IE) 2007-03-08 US disclosed
EP-1698647-A1 POLYMER AND PROCESS FOR PRODUCING POLYMER KANSAI PAINT CO., LTD. (JP) 2006-09-06 EP disclosed
EP-0878482-B1 An active energy ray curable composition comprised of a maleimide derivative and a method for curing the said curable composition DAINIPPON INK & CHEMICALS (JP) 2003-03-26 EP disclosed
US-6410611-B1 COATINGS, SURFACE FINISHES, BINDERS DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-06-25 US disclosed
EP-1073685-A1 WATER COMPATIBLE ENERGY CURABLE COMPOSITIONS CONTAINING MALEIMIDE DERIVATIVES SUN CHEMICAL CORPORATION (US) 2001-02-07 EP disclosed
WO-1999048928-A1 WATER COMPATIBLE ENERGY CURABLE COMPOSITIONS CONTAINING MALEIMIDE DERIVATIVES SUN CHEMICAL CORPORATION (US) 1999-09-30 WO disclosed
EP-0878482-A1 An active energy ray curable composition comprised of a maleimide derivative and a method for curing the said curable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-11-18 EP disclosed
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 US disclosed
US-5084469-A Analgesics ADIR ET COMPAGNIE (FR) 1992-01-28 US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed