Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL3172571 | 1.00 | DNM1 (0.48) | DNM1RAD52NPSR1THRATHRB | |
| Glycinebetaine SCHEMBL3186147 | 1.00 | DNM1 (0.48) | DNM1RAD52NPSR1THRATHRB | |
| Dymanthine SCHEMBL1140094 | 0.95 | DNM1 (0.54) | DNM1RAD52NPSR1THRATHRB | |
| Glycinebetaine SCHEMBL7996911 | 0.95 | DNM1 (0.54) | DNM1RAD52NPSR1THRATHRB | |
| Glycinebetaine SCHEMBL1138405 | 0.95 | DNM1 (0.54) | DNM1RAD52NPSR1THRATHRB | |
| Glycinebetaine SCHEMBL1580653 | 0.86 | BBOX1 (0.40) | BBOX1TSHRALDH1A1MEN1CYP2C19 | |
| Dymanthine SCHEMBL16986517 | 0.83 | DNM1 (0.56) | DNM1RAD52NPSR1TSHRALDH1A1 | |
| Betaine SCHEMBL16986519 | 0.83 | DNM1 (0.56) | DNM1RAD52NPSR1TSHRALDH1A1 | |
| Acetic Acid SCHEMBL10938689 | 0.82 | DNM1 (0.71) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL11028728 | 0.82 | DNM1 (0.71) | DNM1TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662631-B2 | Apparatus which utilizes ultrasonic waves for washing, sanitizing and analyzing bacteria in dispensation injection nozzle | SYSMEX CORPORATION (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7422870-B2 | Bacteria counting method | SYSMEX CORPORATION (JP) | 2008-09-09 | — | — | US | disclosed |
| EP-1405918-B1 | Bacteria counting method, bacteria counting apparatus, and reagent kit for counting bacteria | SYSMEX CORP (JP) | 2007-02-28 | — | — | EP | disclosed |
| EP-1413889-B1 | Analyzer for samples and bacteria | SYSMEX CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-20040096931-A1 | Sample analyzers, bacteria analyzers, and solutions for diluting and cleaning | SYSMEX CORPORATION | 2004-05-20 | — | — | US | disclosed |
| EP-1413889-A2 | Sample analyzers, bacteria analyzers, and solutions for diluting and cleaning | Sysmex Corporation (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-20040067548-A1 | Bacteria counting method, bacteria counting apparatus and reagent kit for counting bacteria | SYSMEX CORPORATION | 2004-04-08 | — | — | US | disclosed |
| EP-1405918-A1 | Bacteria counting method, bacteria counting apparatus, and reagent kit for counting bacteria | Sysmex Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-0811028-A1 | POLYETHER POLYMER, PREPARATION PROCESS AND USE THEREOF | Kao Corporation (JP) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996026233-A1 | POLYETHER POLYMER, PREPARATION PROCESS AND USE THEREOF | KAO CORPORATION (JP) | 1996-08-29 | — | — | WO | disclosed |
| EP-0649834-A1 | Carboxybetaine and sulfobetaine and detergent composition and cosmetic containing the same | KAO CORPORATION (JP) | 1995-04-26 | — | — | EP | disclosed |