Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | ODC1 | P11926 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209148 | 0.82 | — | — | |
| SCHEMBL3260625 | 0.81 | FDPS (0.34) | FDPSPDE3AODC1LMNAKDM4E | |
| SCHEMBL3200130 | 0.77 | FDPS (0.36) | FDPSPDE3A | |
| SCHEMBL3097358 | 0.76 | FDPS (0.44) | FDPSPDE3AODC1LMNAKDM4E | |
| SCHEMBL3097378 | 0.76 | FDPS (0.44) | FDPSPDE3AODC1LMNAKDM4E | |
| SCHEMBL2995482 | 0.72 | FDPS (0.46) | FDPSPDE3AODC1LMNAKDM4E | |
| SCHEMBL2995473 | 0.72 | FDPS (0.46) | FDPSPDE3AODC1LMNAKDM4E | |
| SCHEMBL3263711 | 0.67 | FDPS (0.38) | FDPSPDE3AODC1LMNAKDM4E | |
| SCHEMBL3263725 | 0.67 | FDPS (0.38) | FDPSPDE3AODC1LMNAKDM4E | |
| SCHEMBL3201638 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | disclosed |
| EP-1979366-A2 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | Yu, Ruey J. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007082206-A2 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J (US) | 2007-07-19 | — | — | WO | disclosed |