Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29474944 | 0.98 | PKM (0.42) | PKMTSHRCYP19A1ABCG2ITGB2 | |
| SCHEMBL294470 | 0.98 | PKM (0.42) | PKMTSHRCYP19A1ABCG2ITGB2 | |
| SCHEMBL3260210 | 0.96 | PKM (0.41) | PKMTSHRCYP19A1ABCG2ITGB2 | |
| SCHEMBL21694385 | 0.82 | PKM (0.32) | PKMTSHRCYP19A1 | |
| SCHEMBL7027814 | 0.78 | ITGB2 (0.44) | PKMTSHRCYP19A1ABCG2ITGB2 | |
| SCHEMBL8404598 | 0.73 | ADRA2A (0.51) | CYP19A1PGRKMT2AADRA2ASMN1; SMN2 | |
| SCHEMBL30636720 | 0.73 | ADRA2A (0.51) | CYP19A1PGRKMT2AADRA2ASMN1; SMN2 | |
| SCHEMBL8404596 | 0.73 | CYP19A1 (0.41) | CYP19A1ADRA2AMAOBMAPT | |
| SCHEMBL5541737 | 0.72 | PKM (0.42) | PKMTSHRCYP19A1ABCG2ITGB2 | |
| SCHEMBL276292 | 0.72 | PKM (0.47) | PKMTSHRCYP19A1ABCG2ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344171-B2 | Process for making dihydrocarbyl hydrocarbonphosphonates | ALBEMARLE CORPORATION (US) | 2013-01-01 | — | — | US | disclosed |
| US-20100179342-A1 | PROCESS FOR MAKING DIHYDROCARBYL HYDROCARBONPHOSPHONATES | ALBEMARLE CORPORATION (US) | 2010-07-15 | — | — | US | disclosed |
| EP-2164853-A1 | PROCESS FOR MAKING DIHYDROCARBYL HYDROCARBONPHOSPHONATES | Albermarle Corporation (US) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008154268-A1 | PROCESS FOR MAKING DIHYDROCARBYL HYDROCARBONPHOSPHONATES | ALBEMARLE CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |