Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AOC2 | O75106 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747452 | 1.00 | CYP4F2 (0.47) | CYP4F2CYP4A11CYP3A4CA2HSD11B1 | |
| SCHEMBL3468885 | 0.83 | CYP4F2 (0.52) | CYP4F2CYP4A11HDAC3HDAC1HDAC2 | |
| SCHEMBL9739640 | 0.82 | CYP4F2 (0.67) | CYP4F2CYP4A11CA2HSD11B1TSHR | |
| SCHEMBL7636320 | 0.82 | CYP4F2 (0.67) | CYP4F2CYP4A11CA2HSD11B1TSHR | |
| SCHEMBL7576590 | 0.80 | GAA (0.59) | TSHRGAAALDH1A1HSD17B10HPGD | |
| SCHEMBL4675667 | 0.79 | CYP4F2 (0.50) | CYP4F2CYP4A11CA2HSD11B1HDAC3 | |
| Acetic Acid SCHEMBL20876688 | 0.79 | CYP4F2 (0.62) | CYP4F2CYP4A11CA2HSD11B1TSHR | |
| SCHEMBL11530821 | 0.79 | LMNA (0.47) | CYP4F2CYP4A11CA2HDAC3HDAC1 | |
| SCHEMBL4926783 | 0.77 | CYP4F2 (0.47) | CYP4F2CYP4A11CA2HSD11B1HDAC3 | |
| SCHEMBL5848088 | 0.77 | CYP4F2 (0.47) | CYP4F2CYP4A11CA2HSD11B1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658796-A | USING ENZYME DERIVED FROM SERRATIA | SEPRACHEM, INC. (US) | 1997-08-19 | — | — | US | claimed |
| WO-1996040975-A1 | OPTICAL RESOLUTION OF ALKYL CHROMAN-2-CARBOXYLATES | SEPRACHEM, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| JP-4234871-A | — | — | None | — | — | JP | disclosed |
| EP-1412514-B1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED CARBOXYLIC ESTERS | NOVARTIS AG (CH) | 2010-02-17 | — | — | EP | disclosed |
| US-5658796-A | USING ENZYME DERIVED FROM SERRATIA | SEPRACHEM, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5658796-A | USING ENZYME DERIVED FROM SERRATIA | SEPRACHEM, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| WO-1996040975-A1 | OPTICAL RESOLUTION OF ALKYL CHROMAN-2-CARBOXYLATES | SEPRACHEM, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040975-A1 | OPTICAL RESOLUTION OF ALKYL CHROMAN-2-CARBOXYLATES | SEPRACHEM, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| JP-H04234871-A | INTERMEDIATE FOR PRODUCING 2R-BENZYL-CHROMAN-6-CARBALDEHYDE | PFIZER INC | 1992-08-24 | — | — | JP | disclosed |
| US-5089637-A | PROCESS AND INTERMEDIATES FOR 2R-BENZYL-CHROMAN-6-CARBALDEHYDE | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |