Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.72 |
| ▸ | JAK1 | P23458 | 7/20 | 0.62 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.62 |
| ▸ | JAK2 | O60674 | 7/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144054 | 0.84 | NUDT1 (1.00) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL3601961 | 0.83 | NUDT1 (0.78) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL3200526 | 0.81 | NUDT1 (0.76) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL3264111 | 0.80 | JAK1 (0.60) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL2250300 | 0.80 | NUDT1 (0.73) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL2363033 | 0.80 | NUDT1 (0.73) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL22499606 | 0.80 | NUDT1 (0.73) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL2365482 | 0.79 | NUDT1 (0.68) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL3262251 | 0.79 | NUDT1 (0.71) | NUDT1JAK1EGLN2JAK2JAK3 | |
| SCHEMBL2728166 | 0.79 | JAK2 (0.65) | NUDT1JAK1EGLN2JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010189-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010010189-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |