Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15074544 | 0.83 | RAB9A (0.54) | RPS6KA3NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL15076235 | 0.83 | RPS6KA3 (0.57) | RPS6KA3NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL2732134 | 0.83 | RPS6KA3 (0.54) | RPS6KA3NPC1RAB9AALDH1A1LMNA | |
| Thidiazuron SCHEMBL1808496 | 0.75 | SMN1; SMN2 (0.57) | NPC1RAB9AALDH1A1LMNAKDM4E | |
| Thidiazuron SCHEMBL121077 | 0.75 | SMN1; SMN2 (0.57) | NPC1RAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL11925387 | 0.73 | PTPN1 (0.59) | NPC1RAB9AALDH1A1LMNAKDM4E | |
| Thidiazuron SCHEMBL15553871 | 0.73 | SMN1; SMN2 (0.55) | NPC1RAB9AALDH1A1LMNAKDM4E | |
| Thidiazuron SCHEMBL20723866 | 0.73 | SMN1; SMN2 (0.55) | NPC1RAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL27795863 | 0.73 | RPS6KA3 (0.49) | RPS6KA3 | |
| SCHEMBL892780 | 0.72 | KMT2A (0.71) | NPC1RAB9AALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025870-A1 | SYNERGISTIC COMBINATIONS OF THIADIAZOL CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
| EP-1896417-A1 | LINEAR UREA MIMICS ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | Brystol-Myers Squibb Company (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007002584-A1 | LINEAR UREA MIMICS ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |