Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 9/20 | 0.67 |
| ▸ | NOS3 | P29474 | 8/20 | 0.67 |
| ▸ | NOS1 | P29475 | 5/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | USP7 | Q93009 | 3/20 | 0.35 |
| ▸ | NCF1 | P14598 | 2/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743612 | 0.80 | NOS2 (1.00) | NOS2NOS3NOS1TLR8USP7 | |
| SCHEMBL30664052 | 0.80 | NOS2 (1.00) | NOS2NOS3NOS1TLR8USP7 | |
| SCHEMBL357771 | 0.80 | NOS2 (0.64) | NOS2NOS3NOS1TLR8USP7 | |
| SCHEMBL2555830 | 0.80 | NOS2 (0.48) | NOS2NOS3NOS1USP7NCF1 | |
| SCHEMBL18398543 | 0.80 | NOS2 (0.53) | NOS2NOS3NOS1USP7NCF1 | |
| Hydrochloric Acid SCHEMBL7048556 | 0.78 | NOS2 (0.96) | NOS2NOS3NOS1TLR8USP7 | |
| SCHEMBL18398216 | 0.78 | NOS2 (0.47) | NOS2NOS3NOS1USP7NCF1 | |
| SCHEMBL20673582 | 0.78 | NOS2 (0.62) | NOS2NOS3NOS1TLR8USP7 | |
| SCHEMBL9488515 | 0.78 | NOS2 (0.58) | NOS2NOS3TLR8KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL28159672 | 0.77 | NOS2 (0.46) | NOS2NOS3NOS1TLR8NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153650-A | Amine-substituted aryl or heteroaryl compounds as EHMT1 and EHMT2 inhibitors | EPIZYME股份有限公司 | 2019-01-04 | — | — | CN | disclosed |
| WO-2010059401-A2 | COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS | IRM LLC (BM) | 2010-05-27 | — | — | WO | disclosed |
| US-4931487-A | Chain extenders for polyurethanes | DOW CHEMICAL COMPANY | 1990-06-05 | — | — | US | disclosed |