Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 8/20 | 0.64 |
| ▸ | NOS3 | P29474 | 7/20 | 0.64 |
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18773905 | 0.86 | NOS2 (0.65) | NOS2NOS3NOS1DHFRHTR1A | |
| SCHEMBL3264474 | 0.80 | NOS2 (0.67) | NOS2NOS3NOS1PRKCITLR8 | |
| SCHEMBL3264472 | 0.80 | NOS2 (0.52) | NOS2NOS3NOS1DHFRPRKCI | |
| SCHEMBL20001577 | 0.78 | NOS2 (0.56) | NOS2NOS3NOS1DHFRPRKCI | |
| SCHEMBL27483211 | 0.78 | NOS2 (0.44) | NOS2NOS3NOS1HTR1ATAAR1 | |
| SCHEMBL11743612 | 0.78 | NOS2 (1.00) | NOS2NOS3NOS1PRKCITLR8 | |
| SCHEMBL30664052 | 0.78 | NOS2 (1.00) | NOS2NOS3NOS1PRKCITLR8 | |
| SCHEMBL8134172 | 0.77 | NOS2 (0.47) | NOS2NOS3NOS1DHFRTAAR1 | |
| Hydrochloric Acid SCHEMBL7048556 | 0.77 | NOS2 (0.96) | NOS2NOS3NOS1PRKCITLR8 | |
| SCHEMBL18066852 | 0.77 | NOS2 (0.47) | NOS2NOS3NOS1DHFRPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11412732-B2 | Light-triggered sustained release of pesticides | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2022-08-16 | — | — | US | claimed |
| WO-2022013706-A1 | A PROCESS FOR THE PREPARATION OF L-GLUTAMINE | AUROBINDO PHARMA LIMITED (IN) | 2022-01-20 | — | — | WO | claimed |
| US-9593104-B2 | Process for the preparation of oxazolidinone derivatives | BENOVA LABS PVT. LIMITED (IN) | 2017-03-14 | — | — | US | claimed |
| US-20160039803-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONE DERIVATIVES | BENOVA LABS PVT. LIMITED (IN) | 2016-02-11 | — | — | US | claimed |
| WO-2014141067-A2 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONE DERIVATIVES | BENOVA LABS PVT LIMITED (IN) | 2014-09-18 | — | — | WO | claimed |
| EP-1444222-A1 | TINUVIN P-HINDRED AMINE LIGHT STABILIZER AND DERIVATIVES THEREOF, AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-08-11 | — | — | EP | claimed |
| US-6559311-B1 | A process for preparing a novel Tinuvin P-Hindred Amine Light Stabilizer derivative of the general formula (I) wherein R1 is followed by addition of an hydroxy protecting group and stirring the reaction mixture, and evaporation solvent | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-06 | — | — | US | claimed |
| WO-2003035642-A1 | TINUVIN P-HINDRED AMINE LIGHT STABILIZER AND DERIVATIVES THEREOF, AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-01 | — | — | WO | claimed |
| US-20250084112-A1 | Chemical Compounds Useful for Inhibiting Nav1.8 Voltage-Gated Sodium Channels and Treating Nav1.8 Mediated Diseases | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-03-13 | — | — | US | disclosed |
| US-20240083896-A1 | Nitrogen Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-03-14 | — | — | US | disclosed |
| US-20230416287-A1 | Chemical Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-12-28 | — | — | US | disclosed |
| US-20230103791-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-04-06 | — | — | US | disclosed |
| US-20220233798-A1 | MANUFACTURE AND REMANUFACTURE OF VOLATILE ANAESTHETIC AGENTS USING SUPERCRITICAL FLUIDS | SAGETECH MEDICAL EQUIPMENT LIMITED (GB) | 2022-07-28 | — | — | US | disclosed |
| US-11324903-B2 | To the manufacture and remanufacture of volatile anaesthetic agents using supercritical fluids | SAGETECH MEDICAL EQUIPMENT LIMITED (GB) | 2022-05-10 | — | — | US | disclosed |
| EP-0681580-B1 | PRODRUGS OF ANTIINFLAMMATORY 3-ACYL-2-OXINDOLE-1-CARBOXAMIDES | PFIZER (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0681580-A1 | PRODRUGS OF ANTIINFLAMMATORY 3-ACYL-2-OXINDOLE-1-CARBOXAMIDES. | PFIZER HOSPITAL PROD (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994017061-A1 | PRODRUGS OF ANTIINFLAMMATORY 3-ACYL-2-OXINDOLE-1-CARBOXAMIDES | PFIZER INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| US-5270331-A | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides | PFIZER, INC. (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0217651-A2 | Preparation of organic carbonates | TEXACO DEVELOPMENT CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |
| US-3965100-A | 2,3-Dihydrocyclopenta[d]pyrido[1,2-a]pyrimidin-10(1H)-one and its derivatives | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084112-A1 | Chemical Compounds Useful for Inhibiting Nav1.8 Voltage-Gated Sodium Channels and Treating Nav1.8 Mediated Diseases | SCN8A, SCN1A, SCN10A | NOS2 1665/4885NOS3 1490/4885NOS1 1080/4885 |
| US-11412732-B2 | Light-triggered sustained release of pesticides | DDT, ACHE, CRY1 | NOS2 1382/4885NOS3 1875/4885NOS1 1778/4885 |
| US-20240083896-A1 | Nitrogen Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors | SCN8A, SCN1A, SCN2A | NOS2 225/4885NOS3 184/4885NOS1 189/4885 |
| US-20230103791-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | SCN8A, SCN1A, SCN1B | NOS2 2925/4885NOS3 2570/4885NOS1 2332/4885 |
| US-20160039803-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONE DERIVATIVES | OXA1L, PPOX, AZI2 | NOS2 2264/4885NOS3 2119/4885NOS1 2915/4885 |
| US-20230416287-A1 | Chemical Compounds | SCN8A, TRPV1, SCN10A | NOS2 782/4885NOS3 561/4885NOS1 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.