Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606214 | 0.88 | TP53 (0.60) | TP53CYP3A4FGFR2FGFR3MAOB | |
| Hydrochloric Acid SCHEMBL4932873 | 0.87 | TP53 (0.58) | TP53CYP3A4FGFR2FGFR3MAOB | |
| SCHEMBL920977 | 0.82 | TP53 (0.53) | TP53CYP3A4FGFR2FGFR3MAOB | |
| SCHEMBL3193072 | 0.78 | TP53 (0.49) | TP53CYP3A4FGFR2FGFR3MAOB | |
| SCHEMBL924115 | 0.78 | LTA4H (0.59) | TP53CYP3A4FGFR2FGFR3MAOB | |
| SCHEMBL14478199 | 0.77 | TAAR1 (0.69) | TP53CYP3A4TAAR1 | |
| SCHEMBL20825574 | 0.77 | MAOB (0.49) | MAOBTAAR1NOS1NOS2 | |
| SCHEMBL31538932 | 0.77 | MAOB (0.49) | MAOBTAAR1NOS1NOS2 | |
| SCHEMBL756850 | 0.76 | DHFR (0.51) | MAOBDHFRTAAR1NOS1NOS2 | |
| SCHEMBL7774587 | 0.76 | TAAR1 (0.50) | TP53CYP3A4DHFRCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662960-B2 | Beta-strand mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-02-16 | — | — | US | disclosed |
| EP-1646633-B1 | BETA-STRAND MIMETICS | CHOONGWAE PHARMA CORP (KR) | 2009-04-15 | — | — | EP | disclosed |