Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 5/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262792 | 0.83 | MAPK1 (0.53) | ALDH1A1POLBCYP1A2MAPK1CYP2C19 | |
| SCHEMBL3263786 | 0.82 | POLB (0.46) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3260375 | 0.77 | GRM1 (0.40) | GRM1CYP2E1CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL3263163 | 0.77 | POLB (0.46) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL17358785 | 0.77 | CYP2E1 (0.47) | GRM1CYP2E1CYP2A6POLBCYP3A4 | |
| SCHEMBL3387671 | 0.75 | POLB (0.69) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6342651 | 0.73 | CYP1A2 (0.65) | GRM1CYP2E1CYP2A6ALDH1A1MEN1 | |
| SCHEMBL3263951 | 0.72 | KDM5A (0.43) | ALDH1A1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL17356159 | 0.71 | GRM1 (0.44) | GRM1CYP2E1CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL12647572 | 0.71 | GRM1 (0.49) | GRM1CYP2E1CYP2A6ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |