Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262792 | 0.84 | MAPK1 (0.53) | POLBSMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL3263786 | 0.83 | POLB (0.46) | POLBSMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL3386827 | 0.76 | POLB (0.46) | POLBHPGDALDH1A1L3MBTL1MAPT | |
| SCHEMBL17051085 | 0.76 | POLB (0.57) | POLBSMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL3263163 | 0.75 | POLB (0.46) | POLBSMN1; SMN2HPGDALDH1A1L3MBTL1 | |
| SCHEMBL3264523 | 0.75 | GRM1 (0.40) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL12770967 | 0.74 | POLB (0.64) | POLBSMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL3263195 | 0.74 | POLB (0.62) | POLBSMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL9510331 | 0.73 | POLB (0.61) | POLBSMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL1143474 | 0.71 | CYP1A2 (0.68) | POLBSMN1; SMN2GAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |