Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 6/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265119 | 0.83 | NPSR1 (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL3261571 | 0.82 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1 | |
| SCHEMBL17356159 | 0.80 | GRM1 (0.44) | GRM1CYP2E1CYP2A6CYP3A4PIK3CD | |
| SCHEMBL15824144 | 0.77 | CYP2A6 (0.44) | GRM1CYP2E1CYP2A6CYP3A4MYC | |
| SCHEMBL3262626 | 0.77 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL3264523 | 0.77 | GRM1 (0.40) | GRM1CYP2E1CYP2A6CYP3A4CYP11B2 | |
| SCHEMBL17358785 | 0.77 | CYP2E1 (0.47) | GRM1CYP2E1CYP2A6CYP3A4 | |
| SCHEMBL3386827 | 0.76 | POLB (0.46) | ALDH1A1L3MBTL1 | |
| SCHEMBL16659428 | 0.74 | CYP2A6 (0.44) | GRM1CYP2E1CYP2A6CYP3A4MYC | |
| SCHEMBL3261172 | 0.72 | ALDH1A1 (0.41) | PIK3CDALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |