Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 12/20 | 0.39 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249898 | 0.79 | ROCK2 (0.47) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3249902 | 0.71 | ROCK2 (0.47) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3265658 | 0.66 | ROCK2 (0.52) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3238931 | 0.65 | ROCK2 (0.44) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3250665 | 0.64 | ROCK2 (0.49) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3252024 | 0.63 | ROCK2 (0.50) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3251072 | 0.63 | ROCK2 (0.80) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3238762 | 0.62 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL3247499 | 0.62 | ROCK2 (0.67) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3247491 | 0.62 | ROCK2 (0.55) | ROCK2ROCK1CDC42BPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |