Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654971 | 0.80 | CHRM1 (0.38) | SRCCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4140846 | 0.79 | CHRM1 (0.33) | OR51E2SRCCHRM1AKR1A1CHRM3 | |
| SCHEMBL23754689 | 0.78 | SRC (0.33) | SRCCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2813586 | 0.78 | SRC (0.33) | SRCCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2722766 | 0.76 | SLC22A6 (0.37) | SRC | |
| SCHEMBL9777404 | 0.76 | TDP1 (0.43) | SRCTDP1 | |
| SCHEMBL11360544 | 0.76 | TDP1 (0.43) | SRCTDP1 | |
| SCHEMBL987086 | 0.76 | TDP1 (0.43) | SRCTDP1 | |
| SCHEMBL10698540 | 0.76 | TDP1 (0.43) | SRCTDP1 | |
| SCHEMBL890709 | 0.76 | CHRM1 (0.40) | TGFBR1SRCTP53SLC1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309363-A | PYROLYTIC DECOMPOSITION OF METAL ISETHIONATE CARBOXYLATES TO METAL VINYLSULFONATES | TEXACO INC. (US) | 1982-01-05 | — | — | US | claimed |
| WO-2010025435-A2 | CONTROLLED-RELEASED PEPTIDE FORMULATIONS | GENZYME CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |
| EP-0136899-B1 | AMORPHOUS SULFOPOLYESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-04-19 | — | — | EP | disclosed |
| US-4736066-A | Intermediate for substituted peptide compounds | E. R. SQUIBB & SONS, INC. (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0136899-A2 | Amorphous sulfopolyesters | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4480085-A | Amorphous sulfopolyesters | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
| US-4470973-A | HYPOTENSIVE AGENTS, ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1984-09-11 | — | — | US | disclosed |
| US-4309363-A | PYROLYTIC DECOMPOSITION OF METAL ISETHIONATE CARBOXYLATES TO METAL VINYLSULFONATES | TEXACO INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4309363-A | PYROLYTIC DECOMPOSITION OF METAL ISETHIONATE CARBOXYLATES TO METAL VINYLSULFONATES | TEXACO INC. (US) | 1982-01-05 | — | — | US | disclosed |