SCHEMBL3264640

SCHEMBL3264640

CC(=O)CC1C[C@@H](C(C)C)[C@H](O)C[C@@H]1C

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 3/20 0.43
TRPA1 O75762 2/20 0.43
EPHX1 P07099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3264638 1.00 TRPM8 (0.43) TRPM8TRPA1EPHX1
SCHEMBL15080396 0.79 EPHX1 (0.37) TRPM8TRPA1EPHX1
SCHEMBL12802513 0.79
SCHEMBL12633783 0.79
SCHEMBL12166889 0.72 TRPA1 (0.54) TRPM8TRPA1EPHX1
SCHEMBL28350744 0.71 EPHX1 (0.51) TRPM8TRPA1EPHX1
(-)-(1S,3R,4S,6S)-6-Hydroxymenthol SCHEMBL7043768 0.71 TRPA1 (0.52) TRPM8TRPA1EPHX1
SCHEMBL14392077 0.71 EPHX1 (0.36) TRPM8TRPA1EPHX1
SCHEMBL14669034 0.70 TRPA1 (0.37) TRPM8TRPA1
Menthol SCHEMBL28321221 0.69 TRPM8 (0.72) TRPM8TRPA1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1721943-B1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORP (JP) 2010-05-12 EP disclosed
US-7538149-B2 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2009-05-26 US disclosed
US-20060258776-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJI PHOTO FILM CO., LTD. 2006-11-16 US disclosed
EP-1721943-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2006-11-15 EP disclosed