Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 11/20 | 0.71 |
| ▸ | NAMPT | P43490 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245892 | 0.86 | ROCK2 (0.62) | ROCK2NAMPTROCK1MEN1MAPT | |
| SCHEMBL3240812 | 0.83 | ROCK2 (0.51) | ROCK2ROCK1MEN1ALDH1A1LMNA | |
| SCHEMBL3236915 | 0.83 | ROCK2 (1.00) | ROCK2NAMPTROCK1 | |
| SCHEMBL3249431 | 0.81 | ROCK2 (1.00) | ROCK2NAMPTROCK1 | |
| SCHEMBL3127521 | 0.81 | ROCK2 (1.00) | ROCK2NAMPTHIF1AROCK1MEN1 | |
| SCHEMBL1848820 | 0.78 | ROCK2 (0.64) | ROCK2NAMPTROCK1 | |
| SCHEMBL3246832 | 0.77 | ROCK2 (0.72) | ROCK2NAMPTROCK1 | |
| SCHEMBL1847141 | 0.77 | ROCK2 (0.63) | ROCK2NAMPTROCK1ALDH1A1LMNA | |
| SCHEMBL3245931 | 0.76 | ROCK2 (0.48) | ROCK2ROCK1 | |
| SCHEMBL3132012 | 0.76 | ROCK2 (1.00) | ROCK2NAMPTHIF1AROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |