Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31710662 | 0.73 | KMT2A (0.40) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL3263297 | 0.66 | KDM4E (0.32) | KMT2APKMNPSR1MEN1 | |
| SCHEMBL3263504 | 0.64 | CA12 (0.34) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL23087251 | 0.61 | PRMT5 (0.47) | ALDH1A1MAPT | |
| SCHEMBL21240960 | 0.59 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL19538938 | 0.58 | HDAC8 (0.43) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL29520810 | 0.57 | HDAC3 (0.45) | KMT2AGAAALDH1A1LMNAHSD17B10 | |
| SCHEMBL31192827 | 0.57 | CYP1A2 (0.39) | KMT2APKMNPSR1ALDH1A1LMNA | |
| SCHEMBL693245 | 0.57 | MEN1 (0.35) | KMT2AMEN1POLB | |
| SCHEMBL23248593 | 0.57 | ALDH1A1 (0.46) | KMT2APKMGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |