Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263157 | 0.73 | CA12 (0.30) | — | |
| SCHEMBL3264755 | 0.66 | CA12 (0.33) | MEN1KMT2ANPSR1PKM | |
| SCHEMBL24677206 | 0.65 | L3MBTL1 (0.38) | PTGS2PKM | |
| SCHEMBL13259552 | 0.62 | POLB (0.35) | KDM4EMEN1HPGDKMT2ANPSR1 | |
| SCHEMBL14466825 | 0.60 | POLB (0.41) | KDM4EMEN1HPGDKMT2ANPSR1 | |
| SCHEMBL537595 | 0.58 | SMN1; SMN2 (0.38) | KDM4EMEN1HPGDKMT2ADGAT1 | |
| SCHEMBL21721151 | 0.58 | — | — | |
| SCHEMBL3263504 | 0.57 | CA12 (0.34) | KDM4EMEN1KMT2ANPSR1PKM | |
| SCHEMBL24677205 | 0.57 | BRD9 (0.30) | — | |
| SCHEMBL3262454 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |