Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214843 | 0.93 | GRM2 (0.41) | GRM2PDE4B | |
| SCHEMBL4201416 | 0.90 | PDE4B (0.41) | GRM2PDE4B | |
| SCHEMBL3126155 | 0.87 | GRM2 (0.43) | GRM2PDE4B | |
| SCHEMBL3128977 | 0.86 | ALDH1A1 (0.43) | PDE4B | |
| SCHEMBL3120607 | 0.84 | PDE4B (0.39) | GRM2PDE4B | |
| SCHEMBL3126325 | 0.84 | RXRA (0.38) | PDE4B | |
| SCHEMBL3263662 | 0.83 | TAAR1 (0.43) | TAAR1 | |
| SCHEMBL4196553 | 0.83 | GRM2 (0.40) | GRM2PDE4B | |
| SCHEMBL3129936 | 0.82 | KMT2A (0.39) | GRM2PDE4B | |
| SCHEMBL3121497 | 0.82 | RXRA (0.48) | GRM2PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |