Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.42 |
| ▸ | CA2 | P00918 | 16/20 | 0.42 |
| ▸ | CA9 | Q16790 | 13/20 | 0.42 |
| ▸ | CA12 | O43570 | 12/20 | 0.42 |
| ▸ | CA4 | P22748 | 10/20 | 0.42 |
| ▸ | CA6 | P23280 | 10/20 | 0.42 |
| ▸ | CA7 | P43166 | 10/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 10/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 9/20 | 0.42 |
| ▸ | CA3 | P07451 | 7/20 | 0.42 |
| ▸ | CA5A | P35218 | 6/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500908 | 0.78 | CA1 (0.56) | CA1CA2CA9CA12CA4 | |
| SCHEMBL6038485 | 0.73 | CA1 (0.64) | CA1CA2CA9CA12CA4 | |
| SCHEMBL5014186 | 0.73 | CA1 (0.70) | CA1CA2CA9CA12CA4 | |
| SCHEMBL5245480 | 0.70 | CA1 (0.55) | CA1CA2CA9CA12CA4 | |
| SCHEMBL1807804 | 0.70 | CA1 (0.79) | CA1CA2CA9CA12CA4 | |
| SCHEMBL11130676 | 0.70 | KDM4E (0.46) | CA1CA2CA9CA12CA4 | |
| SCHEMBL5012991 | 0.68 | CA1 (0.49) | CA1CA2CA9CA12CA4 | |
| SCHEMBL1807802 | 0.68 | CA1 (0.47) | CA1CA2CA9CA12CA4 | |
| SCHEMBL2777644 | 0.68 | CA1 (0.47) | CA1CA2CA9CA12CA4 | |
| SCHEMBL2776111 | 0.67 | CA1 (0.65) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004139-A1 | NEW CYCLOALKYLATED BENZOTHIADIAZINE DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2010-01-14 | — | — | WO | disclosed |