Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.49 |
| ▸ | CA2 | P00918 | 13/20 | 0.49 |
| ▸ | CA9 | Q16790 | 11/20 | 0.49 |
| ▸ | CA12 | O43570 | 10/20 | 0.49 |
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | CA6 | P23280 | 4/20 | 0.47 |
| ▸ | CA5A | P35218 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.47 |
| ▸ | CA3 | P07451 | 3/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038490 | 0.89 | CA2 (0.56) | CA1CA2CA9CA12CA4 | |
| Disulfamide SCHEMBL309326 | 0.89 | CA1 (0.61) | CA1CA2CA9CA12CA4 | |
| SCHEMBL8404547 | 0.85 | CA1 (0.42) | CA1CA2CA9CA12CA4 | |
| SCHEMBL11554246 | 0.84 | CA1 (0.50) | CA1CA2CA9CA12CA4 | |
| SCHEMBL3500908 | 0.83 | CA1 (0.56) | CA1CA2CA9CA12CA4 | |
| SCHEMBL11552574 | 0.82 | CA1 (0.48) | CA1CA2CA9CA12CA4 | |
| SCHEMBL11511279 | 0.80 | KDM4E (0.52) | CA1CA2CA9CA12CA4 | |
| SCHEMBL26512818 | 0.79 | TRPV4 (0.38) | CA1CA2CA9CA12L3MBTL1 | |
| SCHEMBL6038485 | 0.78 | CA1 (0.64) | CA1CA2CA9CA12CA4 | |
| SCHEMBL28827972 | 0.78 | ALDH1A1 (0.50) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | claimed |