Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 7/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.50 |
| ▸ | STK17B | O94768 | 2/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066435 | 0.86 | CA2 (0.67) | TNK2CDK1CDK2STK17ASTK17B | |
| SCHEMBL13648524 | 0.85 | TNK2 (0.53) | TNK2CDK1CDK2IGF1RCCNB1 | |
| SCHEMBL5155001 | 0.81 | CA2 (0.51) | TNK2PRKCQCDK1CDK2STK17A | |
| SCHEMBL4068764 | 0.81 | CA2 (0.64) | TNK2CDK1CDK2IGF1RCCNB1 | |
| SCHEMBL13794203 | 0.80 | PRKCQ (0.59) | TNK2PRKCQCDK1CDK2STK17A | |
| SCHEMBL1917777 | 0.80 | PRKCQ (0.71) | PRKCQSTK17ACHEK1 | |
| SCHEMBL3264101 | 0.80 | AURKA (0.54) | TNK2IGF1RSYK | |
| SCHEMBL1916929 | 0.78 | PRKCQ (0.72) | PRKCQCDK1CDK2 | |
| SCHEMBL3265649 | 0.77 | AURKA (0.58) | IGF1RSYK | |
| SCHEMBL1916305 | 0.76 | CHEK1 (0.72) | PRKCQSYKCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025831-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |