Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299076 | 0.81 | CSNK1D (0.34) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298762 | 0.79 | CSNK1D (0.34) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298181 | 0.73 | CSNK1D (0.39) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298537 | 0.72 | ALDH1A1 (0.35) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298845 | 0.70 | AURKA (0.32) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298945 | 0.70 | MAPK1 (0.35) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298569 | 0.70 | MAPK1 (0.46) | KDM4EALDH1A1HPGD | |
| SCHEMBL1298741 | 0.69 | CSNK1D (0.32) | CSNK1DCSNK1E | |
| SCHEMBL1298977 | 0.69 | GPR139 (0.31) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298491 | 0.69 | JAK2 (0.38) | CSNK1DCSNK1EKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002472-A1 | JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2010-01-07 | — | — | WO | claimed |
| WO-2010002472-A1 | JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |