Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497004 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL21332805 | 0.86 | SMN1; SMN2 (0.77) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL15920987 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL13495282 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL4832108 | 0.84 | NPC1 (0.81) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL21333190 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL15921183 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL6676998 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL23273674 | 0.83 | NPC1 (0.52) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL3491679 | 0.83 | ALDH1A1 (0.65) | SMN1; SMN2KMT2ALMNANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |