Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198982 | 0.87 | NPC1 (0.49) | NPC1LMNAPDE4BRAB9AKDM4E | |
| SCHEMBL15436730 | 0.83 | NPC1 (0.46) | NPC1LMNAPDE4BRAB9AKDM4E | |
| SCHEMBL1198694 | 0.83 | NPC1 (0.49) | NPC1LMNARAB9AKDM4EALDH1A1 | |
| SCHEMBL3265402 | 0.83 | SMN1; SMN2 (0.60) | NPC1LMNAPDE4BRAB9AALDH1A1 | |
| SCHEMBL9199014 | 0.83 | LMNA (0.50) | NPC1LMNAPDE4BRAB9AKDM4E | |
| SCHEMBL3261727 | 0.83 | RAB9A (0.50) | NPC1LMNARAB9AKDM4EALDH1A1 | |
| SCHEMBL13462878 | 0.82 | SMN1; SMN2 (0.58) | NPC1LMNAPDE4BRAB9AKDM4E | |
| SCHEMBL1458234 | 0.81 | LMNA (0.51) | NPC1LMNAPDE4BRAB9AKDM4E | |
| SCHEMBL26102129 | 0.81 | LMNA (0.51) | NPC1LMNAPDE4BRAB9AKDM4E | |
| SCHEMBL173434 | 0.79 | NPC1 (0.68) | NPC1LMNARAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761397-B | Benzodiazepine derivatives for the treatment of Respiratory Syncytial Virus (RSV) infection | 辉瑞公司 | 2024-11-05 | — | — | CN | disclosed |
| US-20220409629-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | PFIZER INC. | 2022-12-29 | — | — | US | disclosed |
| EP-4048665-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | Reviral Limited (GB) | 2022-08-31 | — | — | EP | disclosed |
| CN-114761397-A | Benzodiazepine derivatives for the treatment of Respiratory Syncytial Virus (RSV) infection | 瑞威有限公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2021079121-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | ReViral Limited (GB) | 2021-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220409629-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION | GABRA1, GABRA3, CNR1 | NPC1 882/4885LMNA 2278/4885PDE4B 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.