Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265611 | 0.86 | JAK2 (0.39) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1298181 | 0.83 | CSNK1D (0.39) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298945 | 0.79 | MAPK1 (0.35) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298569 | 0.76 | MAPK1 (0.46) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL1298380 | 0.75 | KMT2A (0.40) | CSNK1DCSNK1EKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1298083 | 0.74 | MAPK14 (0.35) | CSNK1DCSNK1EKDM4EALDH1A1CYP1A2 | |
| SCHEMBL1298320 | 0.74 | JAK1 (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL1298642 | 0.73 | KCNK3 (0.40) | KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL3265095 | 0.73 | CSNK1D (0.36) | CSNK1DCSNK1EKDM4EALDH1A1HPGD | |
| SCHEMBL1298537 | 0.72 | ALDH1A1 (0.35) | CSNK1DCSNK1EKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002472-A1 | JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |