SCHEMBL3265642

SCHEMBL3265642

NC(=O)COC(=O)NCC1CCN(c2ccc(-c3ccccc3)cn2)CC1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 16/20 0.51
SKP1 P63208 16/20 0.51
SKP2 Q13309 16/20 0.51
CETP P11597 1/20 0.45
USP30 Q70CQ3 1/20 0.44
FAAH O00519 1/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
KDM1A O60341 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3269094 0.91 CKS1B (0.47) CKS1BSKP1SKP2CETPKDM1A
SCHEMBL3266914 0.86 CKS1B (0.49) CKS1BSKP1SKP2USP30KDM1A
SCHEMBL3266209 0.85 CKS1B (0.44) CKS1BSKP1SKP2CETPKDM1A
SCHEMBL3265671 0.85 DEGS1 (0.49) CKS1BSKP1SKP2FAAHBCHE
SCHEMBL3269155 0.85 CHIT1 (0.42) CKS1BSKP1SKP2CETPKDM1A
SCHEMBL3265598 0.84 CKS1B (0.46) CKS1BSKP1SKP2
SCHEMBL1728812 0.84 CKS1B (0.56) CKS1BSKP1SKP2CETPUSP30
SCHEMBL3266247 0.83 HRH3 (0.46) CKS1BSKP1SKP2KDM1A
SCHEMBL3268917 0.82 CKS1B (0.47) CKS1BSKP1SKP2
SCHEMBL240063 0.82 CKS1B (0.48) CKS1BSKP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120004207-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL-AND PIPERIDINYL-ALKYL CARBAMATES SANOFI-AVENTIS (FR) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004207-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL-AND PIPERIDINYL-ALKYL CARBAMATES CLCN2, CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 CKS1B 1534/4885SKP1 4286/4885SKP2 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.