Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249628 | 0.90 | KIF11 (0.43) | SMN1; SMN2KIF11KMT2AMEN1ALDH1A1 | |
| SCHEMBL6476023 | 0.86 | KIF11 (0.43) | LTA4HSMN1; SMN2KIF11KMT2AMEN1 | |
| SCHEMBL13865454 | 0.79 | PPID (0.55) | LTA4HSMN1; SMN2PPIDKMT2AMEN1 | |
| SCHEMBL30610089 | 0.78 | KIF11 (0.49) | SMN1; SMN2KIF11KMT2AMEN1ALDH1A1 | |
| SCHEMBL14356107 | 0.78 | KIF11 (0.49) | SMN1; SMN2KIF11KMT2AMEN1ALDH1A1 | |
| SCHEMBL10276699 | 0.77 | KIF11 (0.46) | SMN1; SMN2KIF11ALDH1A1LMNAGAA | |
| SCHEMBL4363002 | 0.76 | KIF11 (0.49) | LTA4HSMN1; SMN2KIF11KMT2AMEN1 | |
| SCHEMBL12225852 | 0.76 | KIF11 (0.49) | LTA4HSMN1; SMN2KIF11KMT2AMEN1 | |
| SCHEMBL6854126 | 0.76 | KIF11 (0.42) | SMN1; SMN2KIF11KMT2AMEN1LMNA | |
| SCHEMBL6750468 | 0.76 | KIF11 (0.42) | SMN1; SMN2KIF11KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232157-B1 | NON-AGGREGATING, NON-QUENCHING OLIGOMERS COMPRISING NUCLEOTIDE ANALOGUES; METHODS OF SYNTHESIS AND USE THEREOF | EPOCH BIOSCIENCES INC (US) | 2010-05-05 | — | — | EP | disclosed |