Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635498 | 0.89 | GABRA1 (0.50) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL462306 | 0.87 | CYP3A4 (0.52) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL1064753 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL29648809 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL30390691 | 0.85 | GABRA1 (0.52) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL1950281 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL160980 | 0.85 | GABRA1 (0.52) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL10615737 | 0.83 | GABRA1 (0.78) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL10882070 | 0.83 | GABRA1 (0.60) | GABRA1GABRB2TDP1MAPK1CYP3A4 | |
| SCHEMBL11509303 | 0.83 | GABRA1 (0.60) | GABRA1GABRB2TDP1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 690 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304446-B | Derivatization method of optically active phenylacetylene compound | UNIV HARBIN ENG | 2015-02-25 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-5134189-A | Isocyanate, Imino Compound, Polymeric Binder | MITSUBISHI PAPER MILLS LIMITED (JP) | 1992-07-28 | — | — | US | claimed |
| JP-59135188-A | — | — | None | — | — | JP | disclosed |
| JP-2107477-A | — | — | None | — | — | JP | disclosed |
| JP-59135187-A | — | — | None | — | — | JP | disclosed |
| JP-60262686-A | — | — | None | — | — | JP | disclosed |
| JP-5338356-A | — | — | None | — | — | JP | disclosed |
| JP-3199085-A | — | — | None | — | — | JP | disclosed |
| JP-3199086-A | — | — | None | — | — | JP | disclosed |
| JP-7108759-A | — | — | None | — | — | JP | disclosed |
| US-4239768-A | GASTROINTESTINAL DISORDERS | MCNEILAB, INC. (US) | 1980-12-16 | — | — | US | disclosed |
| US-4229462-A | N-ARYL-N'-(2-IMIDAZOLIDINYLIDENE)UREA | MCNEILAB, INC. (US) | 1980-10-21 | — | — | US | disclosed |
| US-4174398-A | Combating fungi with 1-alkyl-1-(1,3,4-thiadiazol-2-yl)-3-phenyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-4150158-A | Oxadiazindione derivatives useful as insecticides | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4051239-A | METHOD OF USE AND PROCESS FOR PREPARING PHOSPHOROIMINOBENZOYLUREA INSECTICIDES | STAUFFER CHEMICAL COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4046909-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |
| US-4025517-A | 4-Oxo-2-hexahydropyrimidinylidene ureas | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-05-24 | — | — | US | disclosed |
| US-3998958-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-21 | — | — | US | disclosed |
| US-3983135-A | 4-Oxo-2-imidazolidinylidene ureas | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-09-28 | — | — | US | disclosed |