Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.85 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.85 |
| ▸ | HPGD | P15428 | 3/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.85 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576186 | 0.92 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL12018004 | 0.92 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL14343894 | 0.92 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL29457716 | 0.92 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL12016510 | 0.87 | OPRD1 (0.80) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL16226285 | 0.84 | OPRD1 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL4586159 | 0.83 | CYP3A4 (0.84) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL232128 | 0.83 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL4576328 | 0.83 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL4575410 | 0.83 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030681-A2 | THERAPEUTIC AGENTS FOR THE TREATMENT OF DISORDERS CAUSING THE SENSATION OF SUFFOCATION | NEW YORK UNIVERSITY (US) | 2010-03-18 | — | — | WO | disclosed |