Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.83 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.83 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 1/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457716 | 1.00 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL12018004 | 1.00 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL14343894 | 1.00 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL3265985 | 0.92 | CYP3A4 (0.85) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL4586159 | 0.91 | CYP3A4 (0.84) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL2750833 | 0.91 | CYP3A4 (0.84) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL232128 | 0.91 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL4576328 | 0.91 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL232384 | 0.91 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD | |
| SCHEMBL12019442 | 0.91 | CYP3A4 (1.00) | CYP3A4OPRD1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220601-A1 | DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | VERSI GROUP, LLC | 2012-08-30 | — | — | US | claimed |
| US-20070173515-A1 | DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | MOUNT COOK BIOSCIENCES, INC. (US) | 2007-07-26 | — | — | US | claimed |
| US-12584916-B2 | Method for measuring the modulation of the activation of a G protein-coupled receptor with GTP analogues | CISBIO BIOASSAYS (FR) | 2026-03-24 | — | — | US | disclosed |
| US-12522656-B2 | Anti-G-protein alpha antibody | CISBIO BIOASSAYS (FR) | 2026-01-13 | — | — | US | disclosed |
| US-20250376477-A1 | ANALGESIC DELTA OPIOID RECEPTOR BITOPIC LIGANDS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2025-12-11 | — | — | US | disclosed |
| EP-3658913-B1 | METHOD FOR MEASURING MODULATION IN THE ACTIVITY OF A G PROTEIN-COUPLED RECEPTOR | CISBIO BIOASSAYS (FR) | 2024-04-03 | — | — | EP | disclosed |
| WO-2024006977-A1 | ANALGESIC DELTA OPIOID RECEPTOR BITOPIC LIGANDS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-01-04 | — | — | WO | disclosed |
| CN-111164427-B | Method for measuring modulation of G protein coupled receptor activity | CISBIO生物试验公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-116987031-A | Single benzyl isoquinoline alkaloid, preparation method and application thereof, and pharmaceutical composition | 中国科学院大连化学物理研究所 | 2023-11-03 | — | — | CN | disclosed |
| CN-114539242-B | Protoberberine-stephania tetrandra alkaloid dimer and application and preparation thereof | 中国科学院大连化学物理研究所 | 2023-05-30 | — | — | CN | disclosed |
| US-20230135945-A1 | Method for Measuring Modulation in the Activity of a G Protein-Coupled Receptor | CISBIO ASSAYS (FR) | 2023-05-04 | — | — | US | disclosed |
| EP-1469850-A1 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | Ardent Pharmaceuticals, Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1450807-A1 | METHOD OF TREATING DEPRESSION WITH DELTA RECEPTOR AGONIST COMPOUNDS | Ardent Pharmaceuticals, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003057223-A9 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS INC (US) | 2004-04-29 | — | — | WO | disclosed |
| US-20040002503-A1 | Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists | VERSI GROUP, LLC | 2004-01-01 | — | — | US | disclosed |
| WO-2003094853-A2 | COMPOSITIONS AND METHODS FOR COMBATING LOWER URINARY TRACT DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONISTS | ARDENT PHARMACEUTICALS, INC. (US) | 2003-11-20 | — | — | WO | disclosed |
| US-20030186872-A1 | Method of treating sexual dysfunctions with delta opioid receptor agonist compounds | DMK PHARMACEUTICALS CORPORATION | 2003-10-02 | — | — | US | disclosed |
| US-20030144299-A1 | Method of treating depression with delta receptor agonist compounds | DMK PHARMACEUTICALS CORPORATION | 2003-07-31 | — | — | US | disclosed |
| WO-2003057223-A1 | METHOD OF TREATING SEXUAL DYSFUNCTIONS WITH DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| WO-2003037342-A1 | METHOD OF TREATING DEPRESSION WITH DELTA RECEPTOR AGONIST COMPOUNDS | ARDENT PHARMACEUTICALS, INC. (US) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250376477-A1 | ANALGESIC DELTA OPIOID RECEPTOR BITOPIC LIGANDS | OPRD1, OPRK1, OPRM1 | CYP3A4 273/4885OPRD1 1/4885CYP1A2 121/4885 |
| US-20030144299-A1 | Method of treating depression with delta receptor agonist compounds | CHRND, CHRNE, CHRNA3 | CYP3A4 3126/4885OPRD1 9/4885CYP1A2 2383/4885 |
| US-20030186872-A1 | Method of treating sexual dysfunctions with delta opioid receptor agonist compounds | OPRD1, OPRK1, OPRM1 | CYP3A4 804/4885OPRD1 1/4885CYP1A2 656/4885 |
| US-12584916-B2 | Method for measuring the modulation of the activation of a G protein-coupled receptor with GTP analogues | GNAI1, GNAI3, GNB1 | CYP3A4 4714/4885OPRD1 461/4885CYP1A2 4813/4885 |
| US-20070173515-A1 | DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | OPRD1, OPRM1, OPRK1 | CYP3A4 675/4885OPRD1 1/4885CYP1A2 760/4885 |
| US-20040002503-A1 | Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists | OPRD1, OPRK1, OPRM1 | CYP3A4 1595/4885OPRD1 1/4885CYP1A2 688/4885 |
| US-20120220601-A1 | DELTA OPIOID RECEPTOR AGONIST COMPOUNDS | OPRD1, OPRM1, OPRK1 | CYP3A4 675/4885OPRD1 1/4885CYP1A2 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.