Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FUBP1 | Q96AE4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259727 | 0.81 | KDM4E (0.62) | KDM4EL3MBTL1RXFP1ALDH1A1GAA | |
| SCHEMBL3259725 | 0.69 | ALDH1A1 (0.44) | KDM4EL3MBTL1RXFP1ALDH1A1GAA | |
| SCHEMBL14008902 | 0.69 | KDM4E (0.49) | KDM4EL3MBTL1RXFP1ALDH1A1GAA | |
| SCHEMBL12075264 | 0.66 | L3MBTL1 (0.53) | KDM4EL3MBTL1ALDH1A1GAALMNA | |
| SCHEMBL1593531 | 0.65 | ALDH1A1 (0.64) | KDM4EL3MBTL1RXFP1ALDH1A1GAA | |
| SCHEMBL13471700 | 0.64 | ALDH1A1 (0.60) | KDM4EL3MBTL1RXFP1ALDH1A1GAA | |
| SCHEMBL12568259 | 0.64 | ALDH1A1 (0.56) | KDM4EL3MBTL1RXFP1ALDH1A1GAA | |
| SCHEMBL3603965 | 0.64 | ALDH1A1 (0.50) | KDM4EL3MBTL1RXFP1ALDH1A1GAA | |
| SCHEMBL13098073 | 0.63 | TP53 (0.59) | KDM4EL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL2569391 | 0.63 | ALDH1A1 (0.59) | KDM4EL3MBTL1ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010005384-A1 | KETONE PYRIDINE ANALOGUES AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISORDERS | ASTRAZENECA AB (SE) | 2010-01-14 | — | — | WO | disclosed |