Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.76 |
| ▸ | PPM1D | O15297 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32660023 | 0.90 | ALOX15 (0.62) | ALOX15PPM1DSMN1; SMN2HPGDHDAC8 | |
| SCHEMBL15320680 | 0.86 | ALOX15 (1.00) | ALOX15PPM1DTHRBSMN1; SMN2LMNA | |
| SCHEMBL32660001 | 0.86 | ALOX15 (0.62) | ALOX15EPHX1KMT2AL3MBTL1 | |
| SCHEMBL32660002 | 0.85 | ALOX15 (0.54) | ALOX15SMN1; SMN2CYP1A2HPGDHDAC8 | |
| SCHEMBL32660005 | 0.85 | ALOX15 (0.54) | ALOX15SMN1; SMN2CYP1A2HPGDHDAC8 | |
| SCHEMBL32660007 | 0.84 | ALOX15 (0.74) | ALOX15PPM1DTHRBSMN1; SMN2LMNA | |
| SCHEMBL23873670 | 0.84 | ALOX15 (0.53) | ALOX15SMN1; SMN2LMNACYP1A2HPGD | |
| SCHEMBL32660019 | 0.81 | ALOX15 (0.56) | ALOX15KMT2AL3MBTL1 | |
| SCHEMBL15320847 | 0.80 | ALOX15 (0.88) | ALOX15PPM1DSMN1; SMN2LMNAHTT | |
| SCHEMBL15323702 | 0.80 | ALOX15 (0.80) | ALOX15SMN1; SMN2CYP1A2HDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678627-A1 | NOVEL FERROPTOSIS INHIBITORS | Universiteit Antwerpen (BE) | 2026-01-14 | — | — | EP | disclosed |
| EP-4678633-A1 | NOVEL FERROPTOSIS INHIBITORS | Universiteit Antwerpen (BE) | 2026-01-14 | — | — | EP | disclosed |