Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32660005 | 1.00 | ALOX15 (0.54) | ALOX15HDAC8YAP1HCAR3CREBBP | |
| SCHEMBL16579940 | 0.90 | ALOX15 (0.55) | ALOX15HDAC8YAP1HCAR3NPC1 | |
| SCHEMBL15321170 | 0.88 | ALOX15 (0.70) | ALOX15HDAC8YAP1HCAR3NPC1 | |
| SCHEMBL32660025 | 0.88 | ALOX15 (0.70) | ALOX15HDAC8YAP1HCAR3NPC1 | |
| SCHEMBL23873670 | 0.88 | ALOX15 (0.53) | ALOX15HDAC8YAP1HCAR3CREBBP | |
| SCHEMBL22043546 | 0.85 | ALOX15 (0.67) | ALOX15HDAC8YAP1HCAR3ALDH1A1 | |
| SCHEMBL22043531 | 0.85 | ALOX15 (0.67) | ALOX15HDAC8YAP1HCAR3ALDH1A1 | |
| SCHEMBL32660091 | 0.85 | ALOX15 (0.76) | ALOX15HDAC8CREBBPNPC1SMN1; SMN2 | |
| SCHEMBL27218058 | 0.84 | ALOX15 (0.56) | ALOX15HDAC8YAP1HCAR3NPC1 | |
| SCHEMBL15321173 | 0.84 | HCAR3 (0.68) | ALOX15HCAR3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678627-A1 | NOVEL FERROPTOSIS INHIBITORS | Universiteit Antwerpen (BE) | 2026-01-14 | — | — | EP | disclosed |
| EP-4678633-A1 | NOVEL FERROPTOSIS INHIBITORS | Universiteit Antwerpen (BE) | 2026-01-14 | — | — | EP | disclosed |