Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267251 | 0.91 | PPARD (0.52) | PPARDMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL3267254 | 0.91 | PPARD (0.52) | PPARDMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL3280957 | 0.89 | PPARD (0.44) | PPARDMAPTALDH1A1HPGDPOLB | |
| SCHEMBL3270793 | 0.89 | PPARD (0.44) | PPARDMAPTALDH1A1HPGDTP53 | |
| SCHEMBL3270787 | 0.89 | PPARD (0.44) | PPARDMAPTALDH1A1HPGDTP53 | |
| SCHEMBL3266067 | 0.88 | PPARD (0.55) | PPARDMAPTALDH1A1HPGDTP53 | |
| SCHEMBL658629 | 0.84 | PPARD (0.83) | PPARD | |
| SCHEMBL658630 | 0.84 | PPARD (0.83) | PPARD | |
| SCHEMBL3266549 | 0.82 | PPARD (0.52) | PPARDMAPTTP53KMT2ARAB9A | |
| SCHEMBL3267255 | 0.80 | PPARD (0.51) | PPARDMAPTALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558571-B1 | NOVEL COMPOUNDS USEFUL IN TREATING PPAR MEDIATED DISEASES | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-06-02 | — | — | EP | claimed |