Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266067 | 0.91 | PPARD (0.55) | PPARDALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL3267251 | 0.89 | PPARD (0.52) | PPARDALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL3267254 | 0.89 | PPARD (0.52) | PPARDALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL3266552 | 0.86 | PPARD (0.50) | PPARDL3MBTL1HSD17B2HSD17B1ALPL | |
| SCHEMBL659368 | 0.85 | PPARD (0.76) | PPARD | |
| SCHEMBL659367 | 0.85 | PPARD (0.76) | PPARD | |
| SCHEMBL3280960 | 0.81 | PPARD (0.43) | PPARDALDH1A1L3MBTL1KMT2AHSD17B2 | |
| SCHEMBL3270795 | 0.81 | PPARD (0.43) | PPARDL3MBTL1LMNAKMT2AMAPT | |
| SCHEMBL3266065 | 0.80 | PPARD (0.57) | PPARDALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL5959643 | 0.79 | PPARD (0.67) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558571-B1 | NOVEL COMPOUNDS USEFUL IN TREATING PPAR MEDIATED DISEASES | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-06-02 | — | — | EP | claimed |