Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.90 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.90 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.90 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.90 |
| ▸ | BLM | P54132 | 1/20 | 0.90 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.90 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | MTOR | P42345 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15259678 | 0.96 | HPGD (0.97) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL1155582 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL5088067 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL5889449 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL1155739 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL8373082 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL2400979 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| Nonivamide SCHEMBL81939 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL679954 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL29669968 | 0.95 | CYP1A2 (1.00) | HPGDCYP1A2CYP3A4CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099316-B1 | FLAVOUR MODULATING DERIVATIVE OF A CARBOXYLIC ACID AND A PURINE, PYRIMIDINE, NUCLEOSIDE OR NUCLEOTIDE | GIVAUDAN SA (CH) | 2017-06-21 | — | — | EP | disclosed |
| US-20130028846-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2013-01-31 | — | — | US | disclosed |
| US-8293215-B2 | Flavour modulating derivative of a carboxylic acid and a purine, pyrimidine, nucleoside, or nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2012-10-23 | — | — | US | disclosed |
| US-20100074850-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2010-03-25 | — | — | US | disclosed |
| EP-2099316-A1 | FLAVOUR MODULATING DERIVATIVE OF A CARBOXYLIC ACID AND A PURINE, PYRIMIDINE, NUCLEOSIDE OR NUCLEOTIDE | Givaudan Nederland Services B.V. (NL) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008072963-A1 | FLAVOUR MODULATING DERIVATIVE OF A CARBOXYLIC ACID AND A PURINE, PYRIMIDINE, NUCLEOSIDE OR NUCLEOTIDE | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100074850-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | NUDT1, GART, UMPS | HPGD 354/4885CYP1A2 1007/4885CYP3A4 1055/4885 |
| US-20130028846-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | NUDT1, GART, UMPS | HPGD 333/4885CYP1A2 1046/4885CYP3A4 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.