SCHEMBL32660735

SCHEMBL32660735

Nc1ccc(NC(=O)N2CCN(Cc3ccc4[nH]c(-c5ccccn5)nc4c3)CC2)cc1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 19/20 0.51
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.45
HPGD P15428 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19970781 0.92 FAAH (0.57) FAAHKDM4ENPC1ALDH1A1TP53
SCHEMBL32660773 0.92 FAAH (0.57) FAAHKDM4ENPC1ALDH1A1TP53
SCHEMBL19970861 0.89 FAAH (0.57) FAAH
SCHEMBL32660769 0.89 FAAH (0.57) FAAH
SCHEMBL32660770 0.89 FAAH (0.59) FAAHALDH1A1SMN1; SMN2
SCHEMBL32660738 0.89 MEN1 (0.53) FAAHKDM4ENPC1ALDH1A1RAB9A
SCHEMBL32660720 0.87 FAAH (0.59) FAAHKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL32660759 0.86 MAPK1 (0.59) FAAHKDM4ENPC1ALDH1A1HPGD
SCHEMBL32660761 0.85 FAAH (0.57) FAAHKDM4ENPC1ALDH1A1TP53
SCHEMBL19970782 0.85 FAAH (0.57) FAAHKDM4ENPC1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678234-A1 ANTAGONIST HETEROCYCLIC COMPOUNDS INVOLVED IN THE CGAS-STING ROUTE Centre National de la Recherche Scientifique (FR) 2026-01-14 EP disclosed