Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 9/20 | 0.55 |
| ▸ | METAP2 | P50579 | 3/20 | 0.55 |
| ▸ | METAP1 | P53582 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245430 | 1.00 | CBFB (0.55) | CBFBMETAP2METAP1NPC1RAB9A | |
| SCHEMBL19982677 | 0.90 | F2 (0.65) | CBFBMETAP2METAP1NPC1RAB9A | |
| SCHEMBL32660766 | 0.90 | F2 (0.65) | CBFBMETAP2METAP1NPC1RAB9A | |
| SCHEMBL29882822 | 0.85 | CBFB (0.55) | CBFBMETAP2METAP1NPC1RAB9A | |
| SCHEMBL20665788 | 0.85 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL179109 | 0.85 | METAP2 (0.60) | CBFBMETAP2METAP1NPC1RAB9A | |
| SCHEMBL18365269 | 0.84 | METAP2 (0.53) | METAP2NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL1170648 | 0.84 | KDM4E (0.61) | NPC1RAB9ASMN1; SMN2PKMHPGD | |
| SCHEMBL11034496 | 0.84 | METAP1 (0.58) | CBFBMETAP2METAP1NPC1RAB9A | |
| SCHEMBL179156 | 0.84 | CHEK2 (0.67) | CBFBMETAP2METAP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678234-A1 | ANTAGONIST HETEROCYCLIC COMPOUNDS INVOLVED IN THE CGAS-STING ROUTE | Centre National de la Recherche Scientifique (FR) | 2026-01-14 | — | — | EP | disclosed |