Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | CASP1 | P29466 | 3/20 | 0.73 |
| ▸ | CASP7 | P55210 | 3/20 | 0.73 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3325607 | 0.97 | ALDH1A1 (0.69) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL3324986 | 0.97 | KDM4E (0.71) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL3324053 | 0.96 | ALDH1A1 (0.75) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL2846713 | 0.92 | KDM4E (0.64) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL2846711 | 0.92 | KDM4E (0.64) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL3325346 | 0.91 | KDM4E (0.66) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL3320927 | 0.91 | KDM4E (0.82) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL2843210 | 0.90 | LMNA (0.62) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL3328511 | 0.89 | ALDH1A1 (0.66) | ALDH1A1HSD17B10HPGDCASP1CASP7 | |
| SCHEMBL3323371 | 0.89 | ALDH1A1 (0.67) | ALDH1A1HSD17B10HPGDCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056907-A2 | COMPOUNDS THAT INDUCE PANCREATIC BETA-CELL EXPANSION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-05-20 | — | — | WO | claimed |