SCHEMBL32662795

SCHEMBL32662795

COc1ccc(C(=O)/C=C/c2ccc(/C=C3\SC(=O)N(Cc4ccccc4C(=O)O)C3=O)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA9 Q16790 1/20 0.55
▸ PTPN1 P18031 5/20 0.54
▸ PTPN2 P17706 4/20 0.54
▸ ACP1 P24666 4/20 0.54
▸ PTPRF P10586 2/20 0.54
▸ PTPRB P23467 2/20 0.54
▸ MEN1 O00255 4/20 0.51
▸ KMT2A Q03164 4/20 0.51
▸ MAPT P10636 2/20 0.51
▸ MAPK1 P28482 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ ALPL P05186 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ RECQL P46063 1/20 0.51
▸ PPARG P37231 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ HSPD1 P10809 1/20 0.50
▸ TNFRSF1A P19438 1/20 0.50
▸ MAOB P27338 1/20 0.50
▸ HSPE1 P61604 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25196342 0.85 PTPN1 (0.68) CA9PTPN1PTPN2ACP1PTPRF
SCHEMBL15815473 0.81 MAPK1 (0.59) PTPN1PTPN2ACP1PTPRFPTPRB
SCHEMBL15815472 0.81 MAPK1 (0.59) PTPN1PTPN2ACP1PTPRFPTPRB
SCHEMBL15815471 0.81 MAPK1 (0.59) PTPN1PTPN2ACP1PTPRFPTPRB
SCHEMBL25214975 0.79 PTPN1 (0.65) PTPN1PTPN2ACP1PTPRFPTPRB
SCHEMBL25216522 0.78 PTPN1 (0.71) PTPN1PTPN2ACP1PTPRFPTPRB
SCHEMBL25197112 0.76 MAPT (0.65) CA9PTPN1MAPTMAPK1ALDH1A1
SCHEMBL2547330 0.76 PIM1 (0.77) CA9MEN1KMT2AMAPTMAPK1
SCHEMBL2547331 0.76 PIM1 (0.77) CA9MEN1KMT2AMAPTMAPK1
SCHEMBL25191741 0.75 PTPN1 (0.69) PTPN1PTPN2ACP1PTPRFPTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CA9 1508/4885PTPN1 1308/4885PTPN2 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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