Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730329 | 1.00 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DCRHR1 | |
| SCHEMBL32663022 | 0.94 | TRPV1 (0.42) | PDE4APDE4BPDE4CPDE4DCRHR1 | |
| SCHEMBL22730484 | 0.94 | TRPV1 (0.42) | PDE4APDE4BPDE4CPDE4DCRHR1 | |
| SCHEMBL22730143 | 0.89 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DCRHR1 | |
| SCHEMBL32663023 | 0.89 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DCRHR1 | |
| SCHEMBL22716380 | 0.83 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DTRPV1 | |
| SCHEMBL29503848 | 0.83 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DTRPV1 | |
| SCHEMBL22730142 | 0.83 | PDE2A (0.42) | PDE4APDE4BPDE4CPDE4DCRHR1 | |
| SCHEMBL32663017 | 0.83 | PDE2A (0.42) | PDE4APDE4BPDE4CPDE4DCRHR1 | |
| SCHEMBL25237231 | 0.79 | PDE10A (0.44) | PDE4APDE4BPDE4CPDE4DHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528778-B2 | Microbiocidal derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528778-B2 | Microbiocidal derivatives | CCR1, CCR6, CCRL2 | PDE4A 3123/4885PDE4B 3299/4885PDE4C 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.