Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730143 | 0.91 | PDE4A (0.40) | PDE10AHPGDSADORA2AWDR5PDE4A | |
| SCHEMBL32663023 | 0.91 | PDE4A (0.40) | PDE10AHPGDSADORA2AWDR5PDE4A | |
| SCHEMBL32663017 | 0.86 | PDE2A (0.42) | PDE10AHPGDSADORA2APDE4APDE4B | |
| SCHEMBL22730142 | 0.86 | PDE2A (0.42) | PDE10AHPGDSADORA2APDE4APDE4B | |
| SCHEMBL32663019 | 0.79 | PDE4A (0.40) | PDE10AHPGDSADORA2AWDR5PDE4A | |
| SCHEMBL22730329 | 0.79 | PDE4A (0.40) | PDE10AHPGDSADORA2AWDR5PDE4A | |
| SCHEMBL22730134 | 0.77 | TYK2 (0.37) | — | |
| SCHEMBL22716255 | 0.77 | PDE4A (0.44) | PDE10AADORA2AWDR5PDE4APDE4B | |
| SCHEMBL29503754 | 0.77 | PDE4A (0.44) | PDE10AADORA2AWDR5PDE4APDE4B | |
| SCHEMBL30989850 | 0.76 | PDE10A (0.51) | PDE10AHPGDSMAPK1WDR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192628-A1 | MICROBIOCIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192628-A1 | MICROBIOCIDAL DERIVATIVES | MPO, PRF1, MSR1 | PDE10A 2016/4885HPGDS 1222/4885ADORA2A 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.