Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | B3GNT2 | Q9NY97 | 11/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | USP1 | O94782 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32663104 | 1.00 | B3GNT2 (0.52) | B3GNT2USP2ALDH1A1LMNAPOLB | |
| SCHEMBL32663049 | 0.98 | B3GNT2 (0.52) | B3GNT2USP2ALDH1A1LMNAPOLB | |
| SCHEMBL21839375 | 0.76 | B3GNT2 (0.75) | B3GNT2POLBPGR | |
| SCHEMBL20529180 | 0.73 | B3GNT2 (0.57) | B3GNT2ALDH1A1POLBPGR | |
| SCHEMBL32663068 | 0.72 | POLB (0.58) | B3GNT2POLBPGR | |
| SCHEMBL25353254 | 0.70 | DGAT2 (0.51) | ACSS2 | |
| SCHEMBL25351160 | 0.70 | DGAT2 (0.51) | ACSS2 | |
| SCHEMBL25351807 | 0.68 | DGAT2 (0.51) | ACSS2 | |
| SCHEMBL27212769 | 0.68 | DGAT2 (0.46) | ALDH1A1ACSS2 | |
| SCHEMBL5409687 | 0.68 | TDO2 (0.57) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225739-B1 | PREPARATION OF BENZIMIDAZOLONE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-01-21 | — | — | EP | claimed |