SCHEMBL3266413

SCHEMBL3266413

COCC/C(C(=O)O)=C(\CCOC)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
APEX1 P27695 4/20 0.37
TSHR P16473 5/20 0.37
DDAH1 O94760 1/20 0.34
FNTA P49354 3/20 0.33
FNTB P49356 3/20 0.33
LMNA P02545 2/20 0.32
THRB P10828 1/20 0.32
PGGT1B P53609 1/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3266415 1.00 ALDH1A1 (0.46) ALDH1A1APEX1TSHRDDAH1FNTA
SCHEMBL11329510 1.00 ALDH1A1 (0.46) ALDH1A1APEX1TSHRDDAH1FNTA
SCHEMBL6524295 0.87 MGAM (0.39) ALDH1A1APEX1TSHRDDAH1FNTA
SCHEMBL6519149 0.87 TSHR (0.42) ALDH1A1APEX1TSHRDDAH1FNTA
SCHEMBL6519157 0.87 TSHR (0.42) ALDH1A1APEX1TSHRDDAH1FNTA
SCHEMBL6524289 0.87 MGAM (0.39) ALDH1A1APEX1TSHRDDAH1FNTA
SCHEMBL9246383 0.85 ALDH1A1 (0.40) ALDH1A1APEX1TSHRFNTAFNTB
SCHEMBL4538480 0.84 ALDH1A1 (0.54) ALDH1A1TSHRFNTAFNTBLMNA
SCHEMBL10741049 0.84 ALDH1A1 (0.39) ALDH1A1APEX1TSHRDDAH1FNTA
SCHEMBL10741032 0.84 ALDH1A1 (0.39) ALDH1A1APEX1TSHRDDAH1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310530-B1 COATING COMPOSITIONS ARKEMA INC (US) 2016-01-06 EP claimed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP claimed
US-4255547-A A VULCANIZABLE COPOLYMER COMPRISING AN ACRYLIC ACID ESTER, BIS(2-METHOXYETHYL FUMARATE OR MALEATE, AND A HALO- OR EPOXY-CONTAINING UNSATURATED MONOMER; COLD RESISTANCE AMERICAN CYANAMID COMPANY (US) 1981-03-10 US claimed
US-4238577-A VULCANIZABLE ELASTOMERIC COPOLYMERS OF UNSATURATED ESTERS; RESISTANCE TO COLD AND OIL ABSORPTION AMERICAN CYANAMID COMPANY (US) 1980-12-09 US claimed
EP-3494171-A1 FOAM CONTROL COMPOSITIONS COMPRISING SILICONE MATERIALS Dow Silicones Corporation (US) 2019-06-12 EP disclosed
WO-2018024859-A1 FOAM CONTROL COMPOSITIONS COMPRISING SILICONE MATERIALS DOW CORNING CORPORATION (US) 2018-02-08 WO disclosed
EP-2859076-A1 LAUNDRY DETERGENTS The Procter & Gamble Company (US) 2015-04-15 EP disclosed
US-20140352076-A1 LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY 2014-12-04 US disclosed
WO-2013181769-A1 LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 2013-12-12 WO disclosed
US-20130326823-A1 LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY 2013-12-12 US disclosed
US-20130326824-A1 LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY 2013-12-12 US disclosed
EP-2393909-B1 FOAM CONTROL COMPOSITION DOW CORNING (US) 2013-10-16 EP disclosed
US-6521587-B1 Polysiloxane partially substituted with phenyl groups attached through alkyl chain, water insoluble fluid, organosilicon resin and hydrophobic filler; detergents; efficiency DOW CORNING S.A. (BE) 2003-02-18 US disclosed
EP-1075863-A2 Silicone foam control agent DOW CORNING S.A. (BE) 2001-02-14 EP disclosed
EP-1075864-A2 Silicone foam control agent DOW CORNING S.A. (BE) 2001-02-14 EP disclosed
US-4783552-A Bis(2-methoxyisopropyl) maleate DOW CORNING CORPORATION (US) 1988-11-08 US disclosed
US-4255547-A A VULCANIZABLE COPOLYMER COMPRISING AN ACRYLIC ACID ESTER, BIS(2-METHOXYETHYL FUMARATE OR MALEATE, AND A HALO- OR EPOXY-CONTAINING UNSATURATED MONOMER; COLD RESISTANCE AMERICAN CYANAMID COMPANY (US) 1981-03-10 US disclosed
US-4255547-A A VULCANIZABLE COPOLYMER COMPRISING AN ACRYLIC ACID ESTER, BIS(2-METHOXYETHYL FUMARATE OR MALEATE, AND A HALO- OR EPOXY-CONTAINING UNSATURATED MONOMER; COLD RESISTANCE AMERICAN CYANAMID COMPANY (US) 1981-03-10 US disclosed
US-4238577-A VULCANIZABLE ELASTOMERIC COPOLYMERS OF UNSATURATED ESTERS; RESISTANCE TO COLD AND OIL ABSORPTION AMERICAN CYANAMID COMPANY (US) 1980-12-09 US disclosed
US-4238577-A VULCANIZABLE ELASTOMERIC COPOLYMERS OF UNSATURATED ESTERS; RESISTANCE TO COLD AND OIL ABSORPTION AMERICAN CYANAMID COMPANY (US) 1980-12-09 US disclosed