SCHEMBL4538480

SCHEMBL4538480

COCCC/C(C(=O)O)=C(\CCCOC)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
TSHR P16473 3/20 0.43
FNTA P49354 3/20 0.39
FNTB P49356 3/20 0.39
THRB P10828 1/20 0.39
PGGT1B P53609 1/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
HPGD P15428 1/20 0.39
KDM4E B2RXH2 5/20 0.36
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
RECQL P46063 1/20 0.34
ARG1 P05089 1/20 0.34
ARG2 P78540 1/20 0.34
GAA P10253 1/20 0.34
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16112147 0.91 ALDH1A1 (0.47) ALDH1A1TSHRFNTAFNTBTHRB
SCHEMBL3266415 0.84 ALDH1A1 (0.46) ALDH1A1TSHRFNTAFNTBTHRB
SCHEMBL11329510 0.84 ALDH1A1 (0.46) ALDH1A1TSHRFNTAFNTBTHRB
SCHEMBL3266413 0.84 ALDH1A1 (0.46) ALDH1A1TSHRFNTAFNTBTHRB
SCHEMBL6525829 0.83 ALDH1A1 (0.40) ALDH1A1TSHRFNTAFNTBKMT2A
SCHEMBL6525826 0.83 ALDH1A1 (0.40) ALDH1A1TSHRFNTAFNTBKMT2A
SCHEMBL16815745 0.80 ALDH1A1 (0.54) ALDH1A1TSHRKMT2AMEN1HPGD
SCHEMBL82451 0.79
SCHEMBL11890006 0.79 ALDH1A1 (0.48) ALDH1A1TSHRFNTAFNTBKMT2A
SCHEMBL28232517 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3448937-B1 AQUEOUS COATING COMPOSITION DOW SILICONES CORP (US) 2020-10-28 EP disclosed
US-10723891-B2 Aqueous coating composition DOW SILICONES CORPORATION (US) 2020-07-28 US disclosed
EP-2638203-B1 GREASE RESISTANT COATING FOR FIBROUS MATERIALS DOW CORNING (US) 2017-12-27 EP disclosed
WO-2017186586-A1 AQUEOUS COATING COMPOSITION DOW CORNING CORPORATION (US) 2017-11-02 WO disclosed
EP-2638203-A1 GREASE RESISTANT COATING FOR FIBROUS MATERIALS Dow Corning Corporation (US) 2013-09-18 EP disclosed
US-20130189889-A1 Grease Resistant Coating For Fibrous Materials DOW CORNING CORPORATION (US) 2013-07-25 US disclosed
WO-2012064558-A1 GREASE RESISTANT COATING FOR FIBROUS MATERIALS DOW CORNING CORPORATION (US) 2012-05-18 WO disclosed
EP-1499661-A1 ORGANOHYDROGENSILICON COMPOUNDS Dow Corning Corporation (US) 2005-01-26 EP disclosed
WO-2003093349-A1 ORGANOHYDROGENSILICON COMPOUNDS DOW CORNING CORPORATION (US) 2003-11-13 WO disclosed
US-5777047-A Organosiloxane compositions with fluorinated resins curable to silicone elastomers having low weep DOW CORNING CORPORATION (US) 1998-07-07 US disclosed
EP-0851000-A2 Curable adhesive organosilicon compositions DOW CORNING LIMITED (GB) 1998-07-01 EP disclosed
EP-0850994-A1 Resin-containing organosiloxane compositions curable to silicone elastomers DOW CORNING CORPORATION (US) 1998-07-01 EP disclosed
US-5756598-A SEALANT DOW CORNING CORPORATION (US) 1998-05-26 US disclosed
US-5658629-A BASE LAYER HAVING ONE SIDE IMPERVIOUS TO WATER VAPOR AND SILICONE MIGRATION AND SECOND SIDE PERMEABLE TO WATER VAPOR MORGAN ADHESIVES COMPANY (US) 1997-08-19 US disclosed