Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922712 | 0.95 | SCN8A (0.64) | SCN8ACYP1A2CYP2D6CYP2C19NOS1 | |
| SCHEMBL10874778 | 0.84 | SCN8A (0.61) | SCN8ANOS1DPP7CHRM2KDM1A | |
| SCHEMBL409441 | 0.83 | SCN8A (0.56) | SCN8ACYP1A2CYP2D6CYP2C19NOS1 | |
| SCHEMBL410123 | 0.81 | SCN8A (0.57) | SCN8ANOS1DPP7KDM1AMAOA | |
| SCHEMBL2828109 | 0.80 | SCN8A (0.58) | SCN8ACYP1A2CYP2D6CYP2C19NOS1 | |
| SCHEMBL2772974 | 0.80 | SCN8A (0.64) | SCN8ANOS1DPP7CHRM2KDM1A | |
| SCHEMBL18096479 | 0.79 | SCN8A (1.00) | SCN8A | |
| SCHEMBL923530 | 0.78 | GLA (0.49) | SCN8AHRH3GLADRD2DRD3 | |
| SCHEMBL320058 | 0.78 | LOXL2 (0.59) | SCN8ANOS1KDM1AMAOAMAOB | |
| SCHEMBL30471916 | 0.78 | LOXL2 (0.59) | SCN8ANOS1KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS, S.A. (ES) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | PNMT, ABCB1, SNCA | SCN8A 3578/4885CYP1A2 433/4885CYP2D6 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.