SCHEMBL32664352

SCHEMBL32664352

CC1CNCCN1C(=O)c1ccc(F)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 10/20 0.47
HSD11B1 P28845 1/20 0.46
HPGD P15428 2/20 0.46
POLB P06746 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
NPC1 O15118 1/20 0.44
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42
PAK4 O96013 2/20 0.41
DPP4 P27487 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29967082 0.79 GAA (0.49) HSD11B1HPGDMEN1KMT2ADPP4
SCHEMBL29967247 0.79 GAA (0.49) HSD11B1HPGDMEN1KMT2ADPP4
Hydrochloric Acid SCHEMBL3714221 0.78 HPGD (0.48) HSD11B1HPGDMEN1KMT2ADPP4
SCHEMBL31568105 0.77 RXFP1 (0.63) P2RX7HSD11B1HPGDNPC1MEN1
SCHEMBL30671638 0.77 SMN1; SMN2 (0.49) HSD11B1HPGDALDH1A1DPP4
SCHEMBL30671642 0.76 DPP4 (0.55) HSD11B1MEN1ALDH1A1KMT2ADPP4
Hydrochloric Acid SCHEMBL3715997 0.76 SMN1; SMN2 (0.48) HSD11B1HPGDALDH1A1KMT2ADPP4
Hydrochloric Acid SCHEMBL3712824 0.75 DPP4 (0.54) HSD11B1MEN1ALDH1A1KMT2ADPP4
SCHEMBL30691934 0.73 P2RX7 (0.54) P2RX7HSD11B1HPGDNPC1MEN1
SCHEMBL31454276 0.73 P2RX7 (0.54) P2RX7HSD11B1HPGDNPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS CNR1, CDR2, SMN1; SMN2 P2RX7 3218/4885HSD11B1 589/4885HPGD 2805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.